Keywords

• Ibutamoren Mesylate
• MK0677
• 159752-10-0

Quick Details

• ProName: MK0677 Supplier (CAS 159752-10-0) Pur...
• CasNo: 159752-10-0
• Molecular Formula: 624.776
• Appearance: pale white solid
• Application: Research and development in pharmaceut...
• Port: shanghai
• ProductionCapacity: 1-3 Kilogram/Month
• Purity: 99% min
• Storage: Dry storage
• LimitNum: 10 Gram
• Heavy metal: N/A
• N/A: Dry storage

Superiority

Rich Experience in produce;Competitive price;Stable supply ability

        Medi-tech pays great attention to the purity, stability and activity of the products. Medi-tech provide chemical test data, such as HNMR, LC-MS and HPLC of each lot of products.   
Mission and vision 
        Medi-tech’s mission is to provide scientists worldwide an easy access to the most innovative life science reagents, and to help them accelerate their R&D development and make more significant discoveries. 
        Medi-tech’s vision is to be recognized by our clients as one of the best suppliers of inhibitors and intermediates for our superior quality, efficient and cost-effective services.

Details

Ibutamoren mesylate (MK-0677) is an orally active nonpeptide growth hormone (GH) secretagogue.
IC50 Value:
Target: GHSR
Ibutamoren mesylate (MK-0677)  stimulates GH release through a pituitary and hypothalamic receptor that is different from the GH-releasing hormone receptor. MK-677is a drug which acts as a potent, orally active growth hormone secretagogue, mimicking the GH stimulating action of the endogenous hormone ghrelin. It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including growth hormone and IGF-1, but without affecting cortisol levels. It is currently under development as a potential treatment for reduced levels of these hormones, such as in growth hormone deficient children or elderly adults, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly. Ibutamoren mesylate (MK-0677)  also alters metabolism of body fat and so may have application in the treatment of obesity.